INFOGRAPHIC

What Is the GLP-1 Hormone?

Reviewed by Claudia Levi, R.N.
January 27, 2025
GLP-1 noun a hormone that plays an important role in hunger, digestion, and blood sugar regulation. GLP-1 medications mimic this hormone.

GLP-1, or glucagon-like peptide-1, is a hormone that occurs naturally in the body, especially in the gut. It plays an important role in helping to regulate blood sugar and digestion and to control hunger.

GLP-1 stimulates the release of the hormone insulin, which helps the body turn glucose (sugar) into usable energy after you’ve eaten. This can help lower blood sugar. GLP-1 also slows down how quickly food leaves your stomach, which can help suppress your appetite and leave you feeling fuller for longer.

People with type 2 diabetes or obesity often make less GLP-1 hormone, research suggests. For these people, taking a prescribed medication called a GLP-1 receptor agonist may help. These medications are often called GLP-1 RA or GLP-1s for short.

GLP-1 RA medications work by mimicking GLP-1 hormones, amplifying their effects: improved satiety and better control of blood sugar and weight.