How GLP-1 Works in the Body

Reviewed by Tama Porter, M.D.
July 29, 2025

GLP-1 (glucagon-like peptide 1) is a natural hormone released in your gut after eating. It plays a key role in blood sugar control, appetite regulation, and weight management.

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GLP-1’s Role in Diabetes and Weight Management

Reduces appetite

Activates brain regions that make you feel full after eating

Slows digestion

Food empties more slowly, steadying blood sugar leaving you feeling full for longer

Regulates blood sugar

Boosts insulin production and reduces glucagon secretion by the pancreas, regulating blood sugar

Improves glucose control

Less sugar is released from the liver, resulting in better glucose control